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Facl4 acsl4

WebApr 27, 2001 · O60488 · ACSL4_HUMAN Protein Long-chain-fatty-acid--CoA ligase 4 Gene ACSL4 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) … The FACL4 pathway is also important in colon carcinogenesis; the development of selective inhibitors for FACL4 may be a worthy effort in the prevention and treatment of colon cancer. FACL4 up-regulation appears to occur during the transformation from the cancer from adenoma to adenocarcinoma. See more Long-chain-fatty-acid—CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme See more The ACSL4 gene is located on the X-chromosome, with its specific location being Xq22.3-q23. The gene contains 17 exons. ASCL4 encodes a 74.4 kDa protein, FACL4, … See more The most common SNP (C to T substitution) in the first intron of the FACL4 gene is associated with altered FA composition of … See more • Knights KM, Jones ME (1992). "Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs". Biochem. … See more Fatty acid-CoA ligase 4 (FACL4), the protein encoded by the ACSL4 gene, is an acyl-CoA synthetase, which is an essential class of lipid … See more ACSL4 expression is regulated by SHP2 activity. Additionally, ACSL4 interacts with ACSL3, APP, DSE, ELAVL1, HECW2, MINOS1, PARK2, SPG20, SUMO2, TP53, TUBGCP3 See more • Human ACSL4 genome location and ACSL4 gene details page in the UCSC Genome Browser. See more

ACSL4 / FACL4 - LSBio

WebNov 28, 2016 · acsl4的这一角色不仅在mef得到支持，而且在三阴性乳腺癌细胞系mda-mb-157中得到进一步证实。这种乳腺癌细胞中有着较高水平的acsl4，因此对rsl3十分 ... WebMar 21, 2024 · ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X-Linked 63 and Stroke, Ischemic . … how to let go of bitterness and resentment https://qift.net

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid ...

WebFeb 8, 2024 · Acyl-CoA synthetase long-chain family member 4 (ACSL4), which is a key enzyme that regulates lipid composition, has been shown to contribute to the execution of ferroptosis, but its role in I/R ... WebAfter staining with primary antibody ( ACSL4, Abcam, ab155282; NeuN, Servicebio, GB11138; EGFP, Servicebio, GB11602) and fluorescent-tagged secondary antibody, nuclei. (3) Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice Cell Death Discovery December 1, 2024 Bin Yan et al. (4) Metformin alleviates osteoarthritis in mice … WebX-vezana intelektualna nesposobnost odnosi se na medicinske poremećaje povezane sa X-povezanim recesivnim nasljeđivaem koji rezultiraju intelektualnomm invalidnošću . Kao i kod većine X-vezanih poremećaja, muškarci su teže pogođeni nego žene. [1] Žene s jednim zahvaćenim X hromozomom i jednim normalnim X hromosomom obično imaju ... how to let go of estranged daughter

ACSL4 Antibody (F-4) SCBT - Santa Cruz Biotechnology

Category:Anti-FACL4 antibody (ab264397) Abcam

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Facl4 acsl4

Identification of ACSL4 as a biomarker and contributor of …

WebDISEASE: Defects in ACSL4 are the cause of mental retardation X- linked type 63 (MRX63) . Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. ... AB061713 - Homo sapiens FACL4 mRNA ... WebFeb 12, 2024 · ACSL4. acyl-CoA synthetase long chain family member 4. Gene ID: 2182, updated on 12-Feb-2024. Gene type: protein coding. Also known as: ACS4; FACL4; LACS4; MRX63; MRX68; XLID63. See all available tests in GTR for this gene. Go to complete Gene record for ACSL4. Go to Variation Viewer for ACSL4 variants.

Facl4 acsl4

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WebLung ischemia-reperfusion (IR) injury is a common clinical pathology associated with high mortality. Ferroptosis, a novel mode of cell death elicited by iron-dependent phospholipid peroxidation, has been implicated in ischemic events. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is one of the main enzymes in pro-ferroptotic lipid ... WebInvitrogen Anti-ACSL4/FACL4 Monoclonal (HL229), Catalog # MA5-36264. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody …

WebSep 23, 2016 · Here, we show that acyl-CoA synthetase long-chain family member 4 (ACSL4) is required for ferroptotic cancer cell death. Compared with ferroptosis-sensitive … WebFACL4 stained by FACL4 antibody [C3], C-term diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min. Western Blot: FACL4 Antibody [NBP2-16401] - Various whole cell …

WebACSL4. HGNC Family. X-linked mental retardation, Acyl-CoA synthetase family (ACS) Name. acyl-CoA synthetase long-chain family member 4. Description. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution ... WebCharacteristics. Rabbit Polyclonal antibody to FACL4 (acyl-CoA synthetase long-chain family member 4) FACL4 antibody [C3], C-term. Purification. Purified by antigen-affinity chromatography. Immunogen. Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FACL4.

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WebApr 6, 2024 · BackgroundIschemic stroke is the main cause of disability worldwide, leading to a serious socioeconomic burden. Ferroptosis is a non-apoptotic form of programmed cell death and is related to various diseases. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is considered a target of ferroptosis, but its specific role in ischemic stroke … josh holland home teamWebAcyl-CoA synthetase long-chain family member 4 (ACSL4), which is a key enzyme that regulates lipid composition, has been shown to contribute to the execution of ferroptosis, but its role in I/R needs clarification. In the present study, we used rosiglitazone (ROSI) and siRNA to inhibit ischemia/hypoxia-induced ACSL4 in vivo and in vitro. how to let go of emotionally unavailable manWeb16 results for FACL4 Sort by. Clear all Done. Filters. Product types Clear. Primary antibodies (15) Proteins and Peptides (1) Target / Protein Clear. FACL4 (16) … how to let go of control anxietyWebACSL4/FACL4 Polyclonal Antibody for IHC, IP, WB, ELISA Host / Isotype Rabbit / IgG Reactivity human, Mouse and More (3) Applications WB, IP, … how to let go of family members who hurt usWebFeb 12, 2024 · ACSL4. acyl-CoA synthetase long chain family member 4. Gene ID: 2182, updated on 12-Feb-2024. Gene type: protein coding. Also known as: ACS4; FACL4; … how to let go of family membersWeb图2c-d：acsl4低表达的肺腺癌患者的无进展生存期（pfs）和总生存期（os）更差。 作者对tcga数据库中524例肺腺癌患者进行通路富集分析，值得注意的是，gsea和go富集分析 … josh holland wausau wiWeb作为一种凋亡诱导剂，dox对gpx4和facl4的表达影响不大； 由于交联fe3+，芬顿反应活性较低，这两个指标在dgu:fe组和dgu: fe /dox组中的表达略有下降； 在近红外照射后，dgu:fe + l和dgu:fe/dox + l组。这种由释放的fe2+引起较强的芬顿反应，gpx4,facl4表达显著下调。 josh.hollandsworth edwardjones.com